Southwestern Spice-Rubbed Pork Tenderloin

Course Main Course
Cuisine American
Prep Time 5 minutes
Cook Time 30 minutes
Total Time 35 minutes
Servings 6 Servings
Author Prep Day


  • 2 pounds pork tenderloin (each pork tenderloin is typically 1-1.5 pounds)
  • 1 tablespoon chili powder
  • 1 tablespoon cumin
  • 1 tablespoon paprika
  • 1 teaspoon oregano
  • 2 teaspoons salt
  • 1 teaspoon black pepper
  • 2 tablespoons cooking oil (avocado oil, olive oil, etc)


  1. Preheat: oven to 400°F.
  2. Prep: line baking sheet or casserole dish with foil.
  3. Season: mix chili powder, cumin, paprika, oregano, salt and pepper in bowl. Rub mix all over pork.
  4. [optional step] Sear meat for added flavor: add 2 tablespoons oil in a large skillet over medium-high heat. Sear pork for about 5 minutes until browned on all sides. Transfer to baking dish.

  5. Bake: for 15 minutes.
  6. Flip: pork over and bake for 10-15 more minutes or until done. Let rest 10 minutes before cutting pork. The pork will continue to cook as it rests.